Back in June I wrote about the alli first team, the first 400 or so consumers who tried alli. A few of the first team members who appeared in the news, most notably Caryn Eyring, who was featured in People Magazine on July 9, 2007. She told People she'd had only one "alli oops" episode and that alli was forcing her to "eat healthier." (This is a repeated theme, BTW, from alli users.) 

Now you can see Laura, a real alli user (i.e. not a professional actress although she has great stage presence) on TV in a new :30 second spot. It's posted to alli's YouTube channel. For updates from other alli users (including John and Laurie) visit real alli stories on myalli.com. Oh, and you can submit your own alli story here, and chances are, you'll see it on myalli.com.

Odds are, if you are reading this, you probably know what a treatment effect (TE) is and why they can happen. And yes, we have been very open about TEs in our marketing of alli. USA Today even writes about our sense of scatalogical humor.

But is there really a benefit to using a product that could result in treatment effects? Many cynics say no, but new users of alli disagree. Some people have even been rethinking treatment effects. Not because they're unpleasant, but because TEs are keeping them honest. The USA Today article makes that point too.

What do you think? Can treatment effects increase motivation for people really committed to losing weight?

Welcome! alli is the only FDA-approved OTC (over the counter) weight loss product available for overweight adults. You've probably seen our advertising (check out our TV ads on YouTube). The goal of this blog is to have a two-way conversation about weight loss issues. We are going to challenge many people's notions about weight loss. And, we want you to challenge us in return. I encourage you to leave a comment below or on any other entry.

My oops experience...

I hope you'll stick with me - and our other contributing authors - and give us time to find our stride in the blogosphere.

alliFirst Team member Caryn Eyring (left) told People Magazine she's lost 21 pounds since she started taking alli in April, along with "cutting fat [and] doing yoga."

She's quoted in the July 9, 2007 issue of People (page 77) with a post-jail Paris Hilton on the cover. Caryn had one  "alli-oops" episode after eating a chicken with crispy noodles appetizer, according to People. alli, she says in the article, "is forcing me to eat healthier."

Yup, alli will punish cheaters if you don't stick to a low-fat diet. But isn't that the whole point... to encourage a healthier way of eating? As another alliFirst member, Paula Miguel, told People: "If I stopped taking alli today, I would still keep those new habits."

Oh and just a reminder that coverage of the alli program by People Magazine is not an endorsement. 

It's no surprise that there are videos on YouTube (see here) that make fun of alli's potential treatment effects (TEs as they're being called). We loved toilet jokes in kindergarten. And apparently a lot of folks still like them now.

Mainstream media is also fixated on alli's possible side effects. See Google news search results on "glaxosmithkline alli." I find it interesting that this is the "news hook" dominating coverage of alli. For in fact...

1. The folks who are actually using alli seem to have a positive attitude about TEs; i.e. they know they can control them.

2. Treatment effects are avoidable if you watch your diet and limit your fat to 15 grams per meal.

Anecdotal reports from the alliFirst Team members say that run-to-the-toilet episodes are manageable and rather rare. The 400 alliFirst members were recruited in April to try alli so they've been using the product for several months now. Their experience should be a useful guide for others.

(Full disclosure: I'm not currently using alli as I'm not overweight.)

Still don't believe me on TEs? Watch Stand-Up Doctor (who is not affiliated in any way with GlaxoSmithKline). He describes himself as a family physician and weight loss doctor by day and a stand-up comedian at night. He has previously prescribed Xenical, the prescription version of alli (it's twice the dose or 120 mg of Orlistat). He says on the video:

"Even at the prescription dosage although people seemed to get a little gassy and sometimes bloated and even occasionally had diarrhea, I never had a (patient) tell me they had an accident or that they couldn't make it to the bathroom... "

Note: The comments on this blog from the alliFirst Team are uniformly - unnervingly - passionate and positive about using the product. See here and here and here. Yup, I was a bit suspicious as you might be too. But the folks at GSK assure me the alliFirst members have not been coached on what to say. 

They're getting a good deal: a six-month supply of alli (worth about $300) as well as access to private online support communities.

Along with the chance to get up close and personal with the alli brand team. For anyone trying to lose weight, who wouldn't want to join the alliFirst Team?

I was curious how GSK chose the lucky 411 who got to try alli before it became available to the public this week. (You should be able to find alli on shelves tomorrow.)

The inside story on the alliFirst Team

Here's what I found out:

GSK asked Communispace, which runs private online communities (discussion groups), to send out email invitations to become an alliFirst member. A total of about 2000 email invites were sent out.   

463 people qualified to be alliFirst members (i.e. they were at least 15 pounds overweight and willing to commit to a low-fat diet and to an exercise program).

411 of those were selected to join the alliFirst team.

The pool of email invite recipients came from three sources:

- those who had visited QuestionEverything.com and indicated they were interested in learning more about alli

- those who answered the "are you ready?" questions affirmatively on myalli.com

- past members of Partners in Weight Loss (a GSK community for overweight women) who also said they were interested in trying alli when it became available

Typical profile of an alliFirst Team member

A typical member, the GSK folks tell me, is a white woman ages 30 - 39 who wants to lose 16 to 50 pounds. She has attended two to four years of college and her household income is between $50,000 and $100,000.

She has tried other weight loss programs in the past, is highly motivated and has agreed to the alli readiness questions.

Namely, she is willing to do the "hard work" to lose weight gradually, is committed to following a reduced-calorie, low-fat diet with an average of 15 grams of fat per meal AND...

understands that if she takes alli with a meal containing too much fat she may get treatment effects (that's GSK term for side effects) such as gas with oily spotting, loose stools and more frequent stools that may be hard to control.

Yup, these 411 alliFirst members appear to be a hardy group as well as super enthusiastic. Seems like a great marketing move on GSK's part.

In a two-minute video segment on CNBC, pharmaceuticals reporter Mike Huckman throws the fat - literally - on the table. I.e. one of those lumps of plastic fat.

He talks about alli's educational approach to marketing and tells listeners about our new are you losing it? book on sale now.  (You'll find it in retailers like CVS, Rite Aid, Walgreens, Wal-Mart, etc.).

Of course, after interviewing me, he just can't help making fun of how alli works. Oops...